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. 2017 Aug 25;15:162. doi: 10.1186/s12916-017-0924-3

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Schematic representation of modelled NLST-like nodule management protocol. *Growth is calculated as a percentage increase in the diameter vs the diameter at the initial screening. D _cut and Growth _cut indicate the threshold values of the diameter and percentage increase in the diameter that indicate a cancer positive result. D _fup represents low threshold diameter for a follow-up examination