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. 2017 Aug 22;5:e3695. doi: 10.7717/peerj.3695

Table 1. Studies on the difference between the effects of LP and DUP periodization models on muscular hypertrophy: summary of findings and assessment of methodological quality.

Study Publication type Participants Design Study duration Hypertrophy/ lean body mass measurement Findings Methodological qualitya Percentage of the theoretical maximum score for exercise intervention trials
Ahmadizad et al. (2014) Published, peer reviewed 32 young untrained overweight men Random assignment either to a control group (n = 8), or non-periodized (n = 8), a LP (n = 8) or a DUP (n = 8) resistance training program performing 6 different resistance training exercises. A mixture of both free weight and machine based multi-joint and single joint isolation exercises was used. The training was carried out 3 times per week. 8 weeks BIA No significant differences between groups in changes in lean body mass (1.9 % increase for the LP group, 2.0 % increase for the DUP group). 6 75%
Buford et al. (2007) Published, peer reviewed 18 young untrained men and 10 young untrained women Random assignment either to a LP (n = 9), a DUP (n = 10) or a WUP (n = 9) resistance training program performing 14 different resistance training exercises. A mixture of both free weight and machine based multi-joint and single-joint isolation exercises was used. The training was carried out 3 times per week. 9 weeks Chest and thigh circumference (with 7 site skinfolds to control for body fat changes) No significant differences between groups in changes in muscle girth (2.0% increase for the LP group, 0.2% increase for the DUP group in the chest circumference, 6.6% increase for the LP group, 3.7% increase for the DUP group in the thigh circumference). The LP group decreased body fat by 1.3% (5.0%), while the DUP group decreased body fat by 1.4% (6.6%). 6 75%
De Lima et al. (2012) Published, peer reviewed 28 young untrained women Random assignment either to a control group (n = 8), or a LP (n = 10) or a DUP (n = 10) resistance training program performing 16 different resistance training exercises. A mixture of both free weight and machine based multi-joint and single-joint isolation exercises was used. The training was carried out 4 times per week. 12 weeks Triceps, suprailiac and thigh skinfolds No significant differences between groups in changes in lean body mass (4.7% increase for the LP group, 3.5% increase for the DUP group). 6 75%
Foschini et al. (2010) Published, peer reviewed 32 untrained obese adolescents (boys: n = 15, girls: n = 17) Random assignment either to a LP (n = 16) or a DUP (n = 16) resistance training program performing 10 different resistance training exercises. A mixture of both free weight and machine based multi-joint and single-joint isolation exercises was used. Participants additionally performed 30 min of aerobic exercise. The training was carried out 3 times per week. 14 weeks BOD-POD No significant differences between groups in changes in lean body mass (3.4% increase for the LP group, 2.4% increase for the DUP group). 6 75%
Harries, Lubans & Callister (2016) Published, peer reviewed 26 untrained adolescent boys Assignment either to a control group (n = 10), or a LP (n = 8) or a DUP (n = 8) resistance training program performing 11 different resistance training exercises. A mixture of both free weight and machine based multi-joint and single-joint isolation exercises was used. The training was carried out 2 times per week. 12 weeks BIA No significant differences between groups in changes in lean body mass (2.1% decrease for the LP group, 1.0% increase for the DUP group). 7 87%
Inoue et al. (2015) Published, peer reviewed 45 untrained obese adolescents (boys: n = 17, girls: n = 28) Random assignment either to aerobic training, (n = 20), or a LP (n = 13) or a DUP (n = 12) resistance training program performing 10 different resistance training exercises. A mixture of both free weight and machine based multi-joint and single-joint isolation exercises was used. Participants in the LP and DUP groups additionally performed 30 min of aerobic exercise. The training was carried out 3 times per week. 26 weeks BOD-POD No significant differences between groups in changes in lean body mass (7.9% increase for the LP group, 2.6% increase for the DUP group). 5 62%
Kok (2006) Doctoral dissertation 16 young untrained women Random assignment based on the participants squat index (1RMSQ/mass) either to a LP (n = 8) or a DUP (n = 8) resistance training program performing 10 different resistance training exercises. A mixture of both free weight and machine based multi-joint and single-joint isolation exercises was used. The training was carried out 3 times per week. 12 weeks Ultrasound performed on the right rectus femoris No significant differences between groups in changes in muscle thickness (3.2% increase for the LP group, 12.9% increase for the DUP group in the cross sectional area). 5 62%
Kok, Hamer & Bishop (2009) Published, peer reviewed 20 young untrained women Random assignment based on the participants squat index (1RMSQ/mass) either to a LP (n = 10) or a DUP (n = 10) resistance training program performing 10 different resistance training exercises. A mixture of both free weight and machine based multi-joint and single-joint isolation exercises was used. The training was carried out 3 times per week. 12 weeks Ultrasound performed on the right rectus femoris No significant differences between groups in changes in muscle thickness (8.7% increase for the LP group, 14.8% increase for the DUP group in the cross sectional area) 6 75%
Monteiro et al. (2009) Published, peer reviewed 27 young trained men Random assignment either to a non-periodized (n = 9), a LP (n = 9) or a DUP (n = 9) resistance training program performing 15 different resistance training exercises. A mixture of both free weight and machine based multi-joint and single-joint isolation exercises was used. The training was carried out 4 times per week. 12 weeks Biceps, triceps, subscapular, and suprailiac skinfolds No significant differences between groups in changes in lean body mass (1.2% increase for the LP group, 0.3% increase for the DUP group). 5 62%
Prestes et al. (2015) Published, peer reviewed 49 untrained elderly women Random assignment either to a control group (n = 10), or a LP (n = 20) or a DUP (n = 19) resistance training program performing 10 different resistance training exercises. A mixture of both free weight and machine based multi-joint and single joint isolation exercises was used. The training was carried out 2 times per week. 16 weeks DXA No significant differences between groups in changes in lean body mass (1.6% decrease for the LP group, 1.7% increase for the DUP group). 5 62%
Simão et al. (2012) Published, peer reviewed 30 young untrained men Random assignment either to a control group (n = 9), a LP (n = 10) or a to a mixed WUP and DUP (n = 11) resistance training program performing 4 different resistance training exercises: barbell bench press, machine front lat-pull down, machine triceps extension, and the straight-bar standing biceps curl. The training was carried out 2 times per week. 12 weeks Ultrasound performed on the right biceps and triceps No significant differences between groups in changes in muscle thickness (5.7% increase for the LP group, 9.1% increase for the DUP group in the biceps, 0.8% increase for the LP group, 4.3% increase for the DUP group in the triceps). 6 75%
Souza et al. (2014) Published, peer reviewed 31 young untrained men Participants from each quartile according to their quadriceps cross-sectional were randomly assigned to a control group (n = 5), or a non-periodized (n = 9), a LP (n = 9) or a DUP (n = 8) resistance training program performing 2 different resistance training exercises for the lower body: squat and knee extensions. The training was carried out 2 times per week. 6 weeks MRI performed on the dominant leg quadriceps No significant differences between groups in changes in cross-sectional area (4.6% increase for the LP group, 5.2% increase for the DUP group). 6 75%
Spineti et al. (2014) Published, peer reviewed 53 young untrained men Random assignment either to a control group (n = 9), or a LP progressing from large to small (LG) muscle groups (n = 10), a LP progressing from small to large (SG) muscle groups (n = 13), a DUP progressing from large to small (LG) muscle groups (n = 11), a DUP progressing from small to large (SG) muscle groups (n = 10) resistance training program performing 4 different resistance training exercises: biceps curl, triceps extension, lat pull down and bench press. The training was carried out 2 times per week. 12 weeks Ultrasound performed on the right biceps and triceps No significant differences between groups in changes in muscle thickness (5.8% and 3.5% increase for the LP groups, 9.3% and 8.2% increase for the DUP groups in the biceps, 0.6% and 9.0% increase for the LP groups, 4.5% and 6.8% increase for the DUP groups in the triceps) 6 75%

Notes.

a

Denotes the total score on the PEDro scale.

LP
linear periodization
DUP
daily undulating periodization
WUP
weekly undulating periodization
BIA
bio-impedance analysis
BOD-POD
air displacement plethysmography
DXA
dual energy X-ray absorptiometry
MRI
magnetic resonance imaging