The performance (AUC of the ROC curve) of eGFRs from a specific equation to detect a series of cardiovascular TOD.
Notes: (A–C) eGFRs (calculated from CKD-EPI, MDRD and c-aMDRD equations) versus AUC =0.5 have statistical differences with PWV, ABI and UACR. (D and E) The AUCs of eGFR (calculated from aCKD-EPI and cCKD-EPI equations) versus AUC =0.5 have statistical differences with all the listed hypertensive TOD. AUCs were classified by each eGFR equation. AUCs of different TODs are presented as histograms of different colors. The abbreviation for each TOD is under the x-axis. The significance is presented at bottom.
Abbreviations: AUC, area under the curve; ROC, receiver operator characteristic; eGFR, estimated glomerular filtration rate; TOD, target organ damage; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; MDRD, Modification of Diet in Renal Disease; c-aMDRD, Chinese-abbreviated MDRD; PWV, pulse wave velocity; ABI, ankle–brachial index; UACR, urine albumin to creatinine ratio; aCKD-EPI, Asian-modified CKD-EPI; cCKD-EPI, Chinese-modified CKD-EPI; LVH, left ventricular hypertrophy; IMT, intima-media thickness; ACR, albumin to creatinine ratio.