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. Author manuscript; available in PMC: 2017 Aug 25.
Published in final edited form as: Hepatology. 2013 May 14;58(1):304–313. doi: 10.1002/hep.26307

Table 2.

Relationship Between Admission Microparticle Concentration, Clinical Characteristics (A), and Laboratory Variables (B) on Admission for ALI/ALF

A.

Clinical Variable (N) Microparticle Size (μm)

0.15–0.27 0.28–0.35 0.36–0.64 >0.64

Log10MP/mL
Etiology APAP (25) 9.98 ± 1.22 8.83 ± 1.04 7.84 ± 0.81 7.65 ± 0.62
Non-APAP (25) 9.98 ± 1.00 8.98 ± 0.48 8.07 ± 0.38 8.00 ± 0.46*
SIRS N 0–1 (22) 9.68 ± 1.01 8.65 ± 0.53 7.66 ± 0.50 7.71 ± 0.55
2–4 (28) 10.21 ± 1.13 9.11 ± 0.93* 8.19 ± 0.64 7.92 ± 0.57
HE grade 0–2 (26) 9.72 ± 0.98 8.68 ± 0.56 7.71 ± 0.48 7.72 ± 0.50
3–4 (24) 10.25 ± 1.18 9.15 ± 0.96* 8.23 ± 0.69 7.95 ± 0.62
Bleeding No (41) 9.84 ± 0.93 8.77 ± 0.52 7.86 ± 0.53 7.78 ± 0.50
Yes (9) 10.60 ± 1.60 9.50 ± 1.45 8.39 ± 0.91* 8.06 ± 0.82
Thrombosis No (41) 10.01 ± 1.15 8.90 ± 0.86 7.93 ± 0.66 7.83 ± 0.58
Yes (9) 9.84 ± 0.87 8.93 ± 0.49 8.09 ± 0.52 7.83 ± 0.53*
Infection No (37) 9.96 ± 0.93 8.84 ± 0.57 7.88 ± 0.58 7.81 ± 0.50
Yes (13) 10.02 ± 1.53 9.08 ± 1.27 8.17 ± 0.76 7.89 ± 0.74
RRT No (32) 9.83 ± 0.94 8.72 ± 0.57 7.77 ± 0.55 7.69 ± 0.48
Yes (18) 10.24 ± 1.32 9.23 ± 1.05* 8.30 ± 0.65 8.07 ± 0.64*
B.

Laboratory Variables Microparticle Size (μm)

0.15–0.27 0.28–0.35 0.36–0.64 >0.64
Phosphate 0.35 0.52§ 0.52§ 0.51
Bicarbonate −0.06 −0.23 −0.44 −0.14
Creatinine 0.22 0.10 0.31* 0.18
ALT −0.19 −0.32* −0.37 −0.46
Factor VIII 0.07 0.36* 0.34* 0.43
MP-TF activity 0.33* 0.42 0.28 0.22

Numbers in (A) represent log10MP/mL of the indicated size ± SD. Numbers in (B) represent Pearson’s r values, with negative numbers denoting inverse correlation.

*

P ≤ 0.05.

P ≤ 0.01.

P ≤ 0.001.

§

P ≤ 0.0001.