Table 2.
Baseline demographics and clinical characteristics (full-analysis set)
| Characteristics | Hydromorphone group (n=86) | Oxycodone group (n=92) | Total (n=178) |
|---|---|---|---|
| Age (years) | |||
| Mean | 70.1 | 68.4 | 69.2 |
| SD | 10.19 | 9.17 | 9.69 |
| Sex, n (%) | |||
| Male | 47 (54.7) | 61 (66.3) | 108 (60.7) |
| Female | 39 (45.3) | 31 (33.7) | 70 (39.3) |
| Body weight (kg) | |||
| Mean | 51.85 | 54.65 | 53.3 |
| SD | 11.069 | 12.469 | 11.863 |
| Body-mass index (kg/m2), n (%) | |||
| <25 kg/m2 | 72 (83.7) | 83 (90.2) | 155 (87.1) |
| ≥25 kg/m2 | 14 (16.3) | 9 (9.8) | 23 (12.9) |
| Underlying disease (tumor type), n (%) | |||
| Lung | 31 (36) | 25 (27.2) | 56 (31.5) |
| Breast | 6 (7) | 6 (6.5) | 12 (6.7) |
| Gastrointestinal | 26 (30.2) | 39 (42.4) | 65 (36.5) |
| Hepatic–biliary–pancreatic | 12 (14) | 15 (16.3) | 27 (15.2) |
| Urogenital | 10 (11.6) | 6 (6.5) | 16 (9) |
| Others | 1 (1.2) | 1 (1.1) | 2 (1.1) |
| ECOG performance status, n (%) | |||
| 0 | 17 (19.8) | 21 (22.8) | 38 (21.3) |
| 1 | 41 (47.7) | 50 (54.3) | 91 (51.1) |
| 2 | 21 (24.4) | 14 (15.2) | 35 (19.7) |
| 3 | 7 (8.1) | 7 (7.6) | 14 (7.9) |
| 4 | 0 | 0 | 0 |
| Visual analog scale (mm) | |||
| Mean | 53.5 | 52.1 | 52.8 |
| SD | 14.53 | 12.81 | 13.65 |
Abbreviation: ECOG, Eastern Cooperative Oncology Group.