Table 4.
Sleep evaluation (cross-frequency table, full-analysis set)
| Group | Baseline | At completion/discontinuation of treatment
|
||||
|---|---|---|---|---|---|---|
| 0. Very unsatisfactory/did not sleep at all | 1. Markedly unsatisfactory | 2. Slightly unsatisfactory | 3. Satisfactory | Total, n (%) | ||
| Hydromorphone group (n=86) | 0. Very unsatisfactory/did not sleep at all | 0 | 2 | 6 | 4 | 12 (14) |
| 1. Markedly unsatisfactory | 0 | 5 | 9 | 6 | 20 (23.3) | |
| 2. Slightly unsatisfactory | 1 | 6 | 21 | 14 | 42 (48.8) | |
| 3. Satisfactory | 0 | 1 | 6 | 5 | 12 (14) | |
| Total, n (%) | 1 (1.2) | 14 (16.3) | 42 (48.8) | 29 (33.7) | 86 | |
| Oxycodone group (n=92) | 0. Very unsatisfactory/did not sleep at all | 0 | 3 | 2 | 1 | 6 (6.5) |
| 1. Markedly unsatisfactory | 1 | 9 | 16 | 7 | 33 (35.9) | |
| 2. Slightly unsatisfactory | 1 | 6 | 17 | 21 | 45 (48.9) | |
| 3. Satisfactory | 0 | 0 | 0 | 8 | 8 (8.7) | |
| Total, n (%) | 2 (2.2) | 18 (19.6) | 35 (38.0) | 37 (40.2) | 92 | |
Notes: Compared with baseline evaluations, change in sleep in both groups was significantly different (P<0.0001) at end of treatment (Wilcoxon signed-rank test). However, there were no significant (P=0.7683) between-group differences in sleep evaluations (Wilcoxon rank sum test).