. Author manuscript; available in PMC: 2017 Aug 25.

Published in final edited form as: J Biol Rhythms. 2017 May 3;32(3):195–211. doi: 10.1177/0748730417700458

Table 4. Amounts of N-acetyltryptamine, melatonin, and N-acetylserotonin in rhesus macaque pineal and retinal extracts.

Metabolite values are the mean ± S.E.M. for extracts from three tissues removed at the indicated times of day; metabolite values were normalized to the µg of total RNA in each sample.

A) Pineal gland
	Piineal Concentration (pmol/µg RNA)^a
Compound	Dawn	Midday	Dusk	Midnight	Mean†
N-Acetyltryptamine	0.010 ± 0.004	0.012 ± 0.001	0.010 ± 0.003	0.008 ± 0.001	0.010 ± 0.001
N-Acetylserotonin	5.60 ± 4.1	N. D.	3.4 ± 0.8	16.0 ± 13	4.6 ± 2.5
Melatonin	11.9 ± 7.6	4.4 ± 1.7	11.7 ± 5.0	17.1 ± 5.1	11.2 ±2.6

B) Retina
	Retinal Concentration (fmol/ µg RNA)^a
Compound	Dawn	Midday	Dusk	Midnight	Mean^c
N-Acetyltryptamine	1.4 ± 0.5	0.35 ± 0.1	0.30 ± 0.02	0.29^b	0.51 ± 0.20
N-Acetylserotonin	N. D.	N. D.	N. D.	N. D.	N.D.
Melatonin	0.42 + 0.09	2.6^b	N. D.	0.64 + 0.13	0.48 ± 0.21

Pineal and retinal values are presented using different units.

N.D. Compound not detected in assay.

Compound was detected in one of three tissue extracts.

Calculation of mean value is based on 12 determinations; zero was assigned if the compound was not detected.