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. 2017 Aug 25;12(8):e0183448. doi: 10.1371/journal.pone.0183448

Table 3. 5-year and 10-year cumulative CSS and OS of patients with different clinicopathological features.

Cancer-specific survival Overall survival
5-year 10-year Log-rank Test, P 5-year 10-year Log-rank Test, P
Age group
 <50 95.97 93.01 NS 95.4 90.8 <0.001
 50–69 98.13 96.47 95.69 88.86
 > = 70 95.69 95.69 78.87 69.5
County type 2003*
 Metropolitan 96.89 95.46 NS 94.24 88.65 NS
 Non-metropolitan 96.97 90.93 93.1 82.86
Race*
 White 97.63 95.18 0.003 95.08 88.38 0.01
 African American 88.54 88.54 82.94 79.48
 Others 100 100 98.48 94.55
Marital status*
 Married 97.46 94.92 NS 96.03 91.23 0.002
 Divorced 95.66 94.33 90.35 82.33
Primary Site
 Nipple/Central portion 100 88.89 NS 94.59 84.08 NS
 UIQ 98.57 95.39 97.14 94.01
 LIQ 94.5 94.5 94.5 94.5
 UOQ 97.24 94.46 94.96 88.62
 LOQ 100 94.44 91.52 86.43
 OVERLAPPING/UNKNOWN 95.18 95.18 92.67 86.47
 NOS 96.62 96.62 93.82 87.42
T-stage
 Tis 99.6 99.6 <0.001 97.9 93.1 <0.001
 T1 97.81 94.95 96.11 89.6
 T2 90.49 85.18 84.92 75.87
 T3 91.64 83.31 84.28 76.62
N-stage
 N0 98.63 97.44 <0.001 95.68 90.98 <0.001
 N1 89.76 81.28 88.96 72.71
 N2 90.34 90.34 86.04 76.48
 N3 75 75 68.18 68.18
Histology
 In situ carcinoma 99.6 99.6 <0.001 97.9 93.1 0.005
 IDC 93.94 91.26 91.51 87.76
 ILC 97.5 82.03 95.73 69.73
 Others 97.88 95.93 90.64 82.23
Grade
 I 100 98.36 NS 95.61 89.96 NS
 II 97.24 93.66 94.9 86.44
 III 93.99 92.67 92.17 88.75
 IV 97.06 97.06 92.14 83.32
 Unknown 97.94 96.65 94.78 90.57
ER
 Negative 92.39 92.39 NS 90.14 90.14 NS
 Positive 97.29 94.5 94.57 88.24
 Unknown 97.7 96.64 94.3 87.58
PR
 Negative 94.27 93 NS 93.54 86.26 NS
 Positive 97.02 94.17 93.58 89.11
 Unknown 97.95 96.91 94.9 88.32
Radiation therapy
 No 97.79 96.2 <0.001 94.87 89.62 0.013
 Yes 95.49 92.95 92.85 83.87
 Unknown 82.25 65.8 82.25 65.8

ER, estrogen receptor; PR, progesterone receptor; LIQ, lower-inner quadrant; LOQ, lower-outer quadrant; UIQ, Upper-inner quadrant; UOQ, Upper-outer quadrant; NOS, Non otherwise specified.IDC, infiltrating ductal carcinoma; ILC, Invasive lobular carcinoma. NS, Non-significant; CSS, Cancer-specific survival; OS, Overall survival;

* Patients with unknown status were excluded. Separated/Single/Widowed were included in the divorce category.