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. 2017 Aug 25;12(8):e0180609. doi: 10.1371/journal.pone.0180609

Table 2. Characteristics of patients with tinnitus and with or without hyperacusis.

Tinnitus (n = 363) Tinnitus with hyperacusis (n = 118) Statistics (t/x2; p-value; Cohen d)
Background
Referring hospital (university/general hospital/clinic) 65/195/103; 18%/54%/28% 35/64/19; 30%/54%/16% 11.21; 0.004; 0.31
1. Age at visit (years) 61.0 ± 15.8 60.4 ± 15.9 −0.358; 0.653; 0.04
2. Gender (female/male) 190/173; 52%/48% 54/64; 46%/54% 1.54; 0.214; 0.11
3. Handedness (right/left/both) 330/14/14;92%/4%/4% 104/9/5;88%/8%/4% 2.72; 0.28; 0.15
Tinnitus history
5. Tinnitus duration (mouths) 82.9 ± 136.1 84.7 ± 136.8 0.12; 0.90; 0.01
6. Onset style (gradual/abrupt) 156/185; 46%/54% 47/68; 59%/41% 0.83; 0.36; 0.09
7. Onset related events (change in hearing/stress/trauma/others/none) 55/75/21/23; 32%/43%/12%/13% 21/31/7/6; 32%/48%/11%/9% 0.92; 0.82; 0.11
8. Pulsatile (no/yes) 244/92; 73%/27% 64/47; 58%/42% 8.72; 0.003; 0.28
9. Site of tinnitus (right/left/both or within head) 88/96/102/29/6; 27%/30%/32%/9%/2% 25/32/35/9/1; 25%/31%/34%/9%/1% 0.83; 0.94; 0.00
10. Manifestation over time (intermittent/constant) 77/268; 22%/78% 20/92; 18%/82% 1.01; 0.32; 0.09
11. Fluctuating (no/yes) 169/187; 47%/53% 48/69; 41%/59% 1.42; 0.49; 0.10
12. Subjective tinnitus loudness (0–100) 52.0 ± 30.7 64.1 ± 30.1 3.63; <0.001; 0.40
14. Character of tinnitus sound (tone/noise/crickets/others) 96/79/106/27; 31%/26%/34%/9% 22/32/25/11; 24%/36%/28%/12% 5.32; 0.15; 0.63
15. Subjective tinnitus pitch (very high/high/medium/low) 47/91/111/71; 15%/28%/35%/22% 13/44/34/13; 13%/42%/33%/13% 8.82; 0.03; 0.17
16. Subjective tinnitus awareness time (0–100) 65.4 ± 35.4 71.0 ± 33.5 1.49; 0.14; 0.16
17. Subjective tinnitus annoyance (0–100) 40.0 ± 31.9 57.9 ± 33.2 5.03; <0.001; 0.56
18. Treatments (many/
several/one/none)
5/56/84/197; 2%/16%/25%/58% 7/27/31/45; 6%/25%/28%/41% 15.32; 0.002; 0.35
Modifying influences
19. Maskable by music or sound (no/yes/I don't know) 76/163/113; 22%/46%/32% 31/47/37;
27%/41%/32%
1.66; 0.44; 0.05
20. Aggravated by noise (no/yes/I don't know) 183/41/133; 51%/12%/37% 30/39/46; 26%/34%/40% 38.20; <0.001; 0.24
21. Somatic modulation (no/yes) 296/52; 85%/15% 93/20; 82%/18% 0.49; 0.48; 0.07
22. Influence by nap (worsens/reduces/no effect) 14/29/285;4%/9%/87% 10/18/75; 10%/18%/73% 11.38; 0.003; 0.32
23. Influence by sleep (no/yes/I don't know) 120/53/177;34%/15%/51% 23/25/64;
21%/22%/57%
8.48; 0.014; 0.01
24. Influence by stress (worsen/reduces/no effect) 110/13/199;34%/4%/62% 65/1/37;63%/1%/36% 27.52; <0.001; 0.50
Related conditions
26. Hearing impairment (no/yes) 166/182; 48%/52% 26/88; 23%/77% 21.91; <0.001; 0.45
27. Hearing aid (no/yes) 336/23; 94%/6% 107/8; 93%/7% 0.04; 0.84; 0.002
28. Noise intolerance (never/rarely/sometime/usually/always) 261/42/42/3/3;74%/12%/12/%1%/1% 32/13/40/17/9;29%/12%36%/15%/8% 112.9; <0.001; 1.10
30. Headache (no/yes) 263/96; 73%/27% 72/45; 62%/39% 5.82; 0.016; 0.22
31. Vertigo or dizziness (no/yes) 245/116; 68%/32% 63/53; 54%/46% 7.05; 0.008; 0.25
32. Temporomandibular joint complaints (no/yes) 292/53; 85%/15% 86/26; 77%/23% 3.65; 0.056; 0.18
33. Neck pain (no/yes) 252/106; 70%/30% 62/55; 53%/47% 11.92; 0.001; 0.32
34. Other pain (no/yes) 288/65; 82%/18% 80/36; 69%/31% 8.23; 0.004; 0.27
35. Psychiatric problems (no/yes) 336/27; 93%/7% 96/22; 81%/19% 12.22; <0.001; 0.32

Patients with hyperacusis complained more severe tinnitus-related symptom than those without hyperacusis; including subjective tinnitus loudness and annoyance evaluating in this questionnaire, hearing impairment, a headache, vertigo, neck pain, other pain, and psychiatric problem. Meaningful contrasts are defined by p <0.05 and d >0.2 and marked in bold font.