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. 2017 Aug 25;12(8):e0183328. doi: 10.1371/journal.pone.0183328

Table 1. Degree of inter-laboratory agreement (Gwet AC2 index) on the evaluation of embryo variables, by TL and CMA.

  Primo VisionTM EmbryoScopeTM CMA
Gwet 95%CI Gwet 95%CI Gwet 95%CI
NumberPN 0.99 0.99 to 1 0.99 0.98 to 1    
SizePN 0.92 0.86 to 0.97 0.97 0.90 to 1
Opposition2PN 0.89 0.83 to 0.94 0.92 0.86 to 0.97
Direct division 1 to 3 cells 0.87 0.78 to 0.97 0.88 0.77 to 0.99
Direct division 3 to 5 cells 0.83 0.74 to 0.93 0.90 0.81 to 1
Fragmentation 0.83 0.78 to 0.88 0.91 0.87 to 0.95 0.95 0.92 to 0.98
Multinucleation 2–4 cell stage 0.70 0.61 to 0.79 0.94 0.90 to 0.97 0.92 0.86 to 0.98
False cleavage 0.69 0.53 to 0.84 0.77 0.62 to 0.93    
Vacuoles 0.58 0.41 to 0.76 0.57 0.36 to 0.79 0.99 0.99 to 1
Asymmetry 0.39 0.22 to 0.55 0.40 0.25 to 0.54 0.54 0.44 to 0.64

PN: pronuclei