Table 3. Results of DIANA-mirath using seven miRNAs identified.
Top 10 significant KEGG pathway was presented. gene: number of genes overlapped with miRNAs target genes, miRNA: number of overlapped miRNAs. Numbers both sides of “/” correspond to type I/type II tensors, respectively.
| KEGG pathway | FDR q-value | gene | miRNA |
|---|---|---|---|
| MicroRNAs in cancer | 3.29E-88/4.68E-68 | 115/141 | 7/22 |
| Proteoglycans in cancer | 5.36E-12/9.48E-17 | 116/159 | 7/22 |
| Cell cycle | 1.26E-10/2.61E-12 | 80/104 | 7/22 |
| Renal cell carcinoma | —/2.25E-011 | —/61 | —/22 |
| Protein processing in endoplasmic reticulum | —/3.81E-10 | —/134 | —/22 |
| Hepatitis B | 6.57E-09/5.37E-09 | 79/107 | 7/22 |
| Prion diseases | 5.14E-08/— | 16/— | 7/— |
| Central carbon metabolism in cancer | 2.76E-07/— | 42/— | 7/— |
| Hippo signaling pathway | 3.27E-07/2.40E-07 | 78/109 | 7/22 |
| Chronic myeloid leukemia | —/2.40E-07 | —/62 | —/22 |
| Viral carcinogenesis | —/2.40E-07 | —/158 | —/22 |
| Pancreatic cancer | —/1.84E-06 | —/55 | —/22 |
| Lysine degradation | 1.15E-06/— | 27/— | 6/— |
| FoxO signaling pathway | 2.89E-06/— | 79/— | 7/— |
| Prostate cancer | 4.52E-06/— | 56/— | 7/— |