Table 4.
The log change (log10 CFU/mL) between the combinations vs. initial inoculum and the most active single agent after 24 h of incubation.
| Colony changes (log10 CFU/mL) at 24 h |
|||||
|---|---|---|---|---|---|
| ATCC 29213 | ATCC 43300 | N54 | N9 | ||
| VAL+TET | vs. initital inoculum | –3.37 | –6.19 | –5.71 | –4.15 |
| vs. most active drug | –2.35 | –4.26 | –3.78 | –3.13 | |
| TIA+TET | vs. initital inoculum | –5.24 | –6.30 | –3.21 | –3.65 |
| vs. most active drug | –4.04 | –5.03 | –2.91 | –3.41 | |
| RET+ TET | vs. initital inoculum | –4.44 | –5.87 | –3.71 | –4.72 |
| vs. most active drug | –2.84 | –3.94 | –2.85 | –4.35 | |
Valnemulin (VAL), tiamulin (TIA), retapamulin (RET), and tetracycline (TET). 1/2 × MICs of all antibiotics were used in this assay.