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(a) In vitro binding of targeted BNFs (Table 2, formulation 5) to PSMA+ PC3 PIP and PSMA− PC3 flu cells following conjugation with various molar equivalences of urea to BNF surface amines (indicated on top of each set), demonstrating preferential uptake in the PSMA+ PC3 PIP cells compared to PSMA− PC3 flu cells; (b) quantification of cellular uptake in each case.
