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. 2017 Aug 28;15:67. doi: 10.1186/s12915-017-0407-1

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© Sanders et al. 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — A neuronal deficiency underlies the post-deprivation slowdown of feeding. a Box plots of pumping rates for 5-HT-triggered pumping in undisrupted and deprived daf-16(mgDf50), ubl-5, and ser-1 mutants. b Left: distributions of pumping rates for deprived and control daf-16 mutants where neuronal function of DAF-16 was restored. Arrow points to the indistinguishable left tails of the distributions, indicating similar statistics of sporadic pumping. Right: mean pumping rates under these conditions. Horizontal lines, boxes, and bars depict medians, 1^st and 3^rd quartiles, and 5th and 95th percentiles, respectively. Sample sizes are noted in parentheses; asterisks and double asterisks denote significant differences (p < 0.05 and p < 0.01, respectively)