Table 2.

Age adjusted estimates of annual relative percentage changes in rates of coronary events

			Age adjusted annual relative percentage change (95% CI)*
Event rate	Total person years at risk	No of events	Entire 20 year period (1978-80 to 1998-2000)	Final 10 year period (1988-90 to 1998-2000)
All major coronary events:	138 111	1561	−3.6 (−4.8 to −2.4, P<0.001)	−3.6 (−6.3 to −0.9)
Coronary heart disease death	138 111	751	−4.8 (−6.5 to −3.1, P<0.001)
Non-fatal definite myocardial infarction	138 111	810	−3.0 (−4.6 to −1.4, P<0.001)
First major coronary event	128 916	1141	−3.5 (−4.8 to −2.1, P<0.001)
Recurrent major coronary events	9195	420	−3.9 (−6.1 to −1.7, P<0.001)
First diagnosed angina:	126 228	1087	2.6 (1.1 to 4.0, P<0.001)	2.9 (−0.3 to 6.2)
Uncomplicated angina	121 332	840	2.4 (0.8 to 4.1, P=0.003)
Angina after myocardial infarction	4896	247	5.1 (2.1 to 8.2, P<0.001)
First diagnosed coronary heart disease	121 024	1816	−0.8 (−1.8 to 0.3, P=0.18)	−0.4 (−2.9 to 2.2)

^*Estimates obtained using Poisson regression, with generalised estimating equation estimates for the following end points: all major coronary heart disease events, non-fatal myocardial infarction, recurrent major coronary events. Adjusted for age and age squared (all end points) and age cubed (all major coronary events, first major coronary event, and first diagnosed coronary heart disease for 20 year follow-up).