Table 3.
Variable | Cochrane systematic reviews (n=809) | Paper based systematic reviews (n=156) | Difference between proportions (95% CI) | P value (χ2 test) |
---|---|---|---|---|
Quality components*: | ||||
Allocation concealment | 639 (79.0) | 37 (23.7) | 55.3 (48.0 to 62.5) | <0.0001 |
Any type of blinding | 604 (74.7) | 64 (41.0) | 33.7 (25.4 to 41.9) | <0.0001 |
Generation of allocation sequence | 209 (25.8) | 26 (16.7) | 9.1 (2.6 to 15.8) | 0.0146 |
Similarity of groups at baseline | 142 (17.6) | 17 (10.9) | 6.7 (1.1 to 12.2) | 0.0402 |
Description of outcomes | 110 (13.6) | 14 (9.0) | 4.6 (−0.5 to 9.7) | 0.1142 |
Intention to treat analysis | 240 (29.7) | 19 (12.2) | 17.5 (11.5 to 23.5) | <0.0001 |
Sample size | 99 (12.2) | 24 (15.4) | −3.2 (−9.2 to 3.0) | 0.2805 |
Losses to follow-up | 561 (69.3) | 52 (33.3) | 36.0 (28.0 to 44.1) | <0.0001 |
Quality scale: | ||||
Schulz | 37 (4.6) | 2 (1.3) | 3.3 (1.0 to 5.6) | 0.0560 |
Jadad | 84 (10.4) | 29 (18.6) | −8.4 (−14.9 to −2.0) | 0.0025 |
Cochrane Group | 133 (16.4) | 0 (0) | 16.4 (13.9 to 19.0) | <0.0001 |
Other | 35 (4.3) | 20 (12.8) | −8.5 (−13.9 to −3.1) | <0.0001 |
More than one answer possible.