Table 2.
Global gene expression is significantly affected by MKP3 expression.
| Probeset ID | Genetitle | Expression level (naïve PC12) Arbitrary unit (Average is 200) |
Log ratio | Fold change |
|---|---|---|---|---|
| 1387138_at | tachykinin 2 | 3005 | 5.7 | 52.0 |
| 1393783_at | similar to contactin associated protein-like 2a | 229 | 5.7 | 52.0 |
| 1371527_at | epithelial membrane protein 1 | 1803 | 5.8 | 53.8 |
| 1393281_at | caveolin 1 | 1003 | 5.8 | 53.8 |
| 1370562_at | calcitonin-related polypeptide, beta | 1455 | 5.9 | 59.7 |
| 1372190_at | aquaporin 4 | 225 | 6.1 | 66.3 |
| 1374235_at | regulator of calcineurin 2 | 180 | 6.1 | 66.3 |
| 1384262_at | protein phosphatase 1, regulatory subunit 3B | 920 | 6.3 | 76.1 |
| 1370907_at | beta-galactosamide alpha-2,6-sialyltranferase 1 | 790 | 6.3 | 78.8 |
| 1377642_at | caveolin 2 | 490 | 6.4 | 81.6 |
| 1398398_at | Homeo box A10 | 1232 | 6.4 | 84.4 |
| 1387316_at | chemokine (C-X-C motif) ligand 1 | 1457 | 6.6 | 93.7 |
| 1370650_s_at | bradykinin receptor B2 | 329 | 6.6 | 93.7 |
| 1386890_at | S100 calcium binding protein A10 | 5145 | 6.8 | 111.4 |
| 1370247_a_at | peripheral myelin protein 22 | 7057 | 6.9 | 119.4 |
| 1370334_at | pleckstrin homology domain containing (evectins) | 4960 | 7.1 | 132.5 |
| 1375170_at | S100 calcium binding protein A11 (calizzarin) | 3233 | 7.2 | 142.0 |
| 1367614_at | annexin A1 | 7899 | 7.2 | 147.0 |
| 1367949_at | proenkephalin | 2983 | 7.5 | 181.0 |
| 1369814_at | chemokine (C-C motif) ligand 20 | 5677 | 7.7 | 207.9 |
RNA was isolated from naïve and MKP3 expressing cells and analyzed with Affymetrix GeneChip Rat Genome 230 2.0 Arrays. Affymetrix’s microarray analysis suite (MAS 5.0 statistical algorithm) was used to analyze the data. Expression level in arbitrary units with 200 being the expression level of an average gene and the log ratio difference in expression between the two cell lines reported by the software is displayed. The log ratio was converted to fold change by the formula: 2(log ratio).