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Effects of different treatments at 12 months of therapy on MV production (A), on purinergic P2X7 receptor (P2X7R) (B), and interleukin-1β (IL-1B) (C) expression: comparison between interferon-beta (IFNb), teriflunomide, and fingolimod (*p < 0.05; **p < 0.01; ***p < 0.001).
