Table 1.
CIP |
LVX |
PMB |
GEN |
OFX |
CXM |
CHL |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PAO1 MOI | 100% | 50% | 100% | 50% | 100% | 50% | 100% | 50% | 100% | 50% | 100% | 50% | 100% | 50% |
1 | > 1; < 10 | >0.1; < 1 | 10 | > 1; < 10 | 10 | 1 | 10 | > 1; < 10 | 50 | 10 | >200 | 200 | >200 | >200 |
10 | 10 | 1 | 10 | > 1; < 10 | 10 | 1 | 50 | 10 | 50 | 10 | >200 | 200 | >200 | >200 |
100 | 10 | 1 | 10 | > 1; < 10 | 10 | 1 | 50 | 10 | 50 | 10 | >200 | 200 | >200 | >200 |
Bacterial growth was recorded by measuring optical density (λ600nm) over time in a broth dilution assay. The concentrations of antibiotics shown (units = μg/mL) are the lowest concentrations that reduced optical density readings at 24 h completely (100%) and by 50%.