Table 2.
Lactobacillus plantarum CIP104448 (CIP48): 10 most upregulated and downregulated genes.
| Gene name | IBMT p-value | Mean fold versus placebo | |
|---|---|---|---|
| Top 10: upregulated genes placebo versus CIP48 | |||
| Coiled-coil domain containing 59 | CCDC59 | 0.01 | 1.33 |
| Aldehyde dehydrogenase 1 family, member L2 | ALDH1L2 | 0.03 | 1.32 |
| KIAA0125 | KIAA0125 | 0.00 | 1.31 |
| Phospholipase C, beta 4 | PLCB4 | 0.01 | 1.31 |
| Coiled-coil domain containing 102B | CCDC102B | 0.04 | 1.29 |
| RAS guanyl releasing protein 3 (calcium and DAG-regulated) | RASGRP3 | 0.03 | 1.28 |
| Peptidase domain containing associated with muscle regeneration 1 | PAMR1 | 0.00 | 1.28 |
| DEP domain containing 1 | DEPDC1 | 0.01 | 1.28 |
| Phospholipase A2, group IIA (platelets, synovial fluid) | PLA2G2A | 0.02 | 1.28 |
| Heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 | HS3ST3B1 | 0.04 | 1.28 |
| Top 10: downregulated genes placebo versus CIP48 | |||
| Potassium channel, subfamily K, member 15 | KCNK15 | 0.05 | −1.33 |
| Transient receptor potential cation channel, subfamily V, member 6 | TRPV6 | 0.01 | −1.33 |
| Long intergenic non-protein coding RNA 282 | LINC00282 | 0.03 | −1.35 |
| Ephrin-A1 | EFNA1 | 0.02 | −1.38 |
| Matrix metallopeptidase 10 (stromelysin 2) | MMP10 | 0.05 | −1.41 |
| Angiopoietin-like 4 | ANGPTL4 | 0.03 | −1.47 |
| Heme oxygenase (decycling) 1 | HMOX1 | 0.00 | −1.50 |
| Nuclear factor, interleukin 3 regulated | NFIL3 | 0.01 | −1.52 |
| Major facilitator superfamily domain containing 2A | MFSD2A | 0.02 | −1.59 |
| Glucose-6-phosphatase, catalytic subunit | G6PC | 0.02 | −1.65 |