Table 3.
Lactobacillus plantarum TIFN101 (TIFN101): 10 most upregulated and downregulated genes.
| Gene name | IBMT p-value | Mean fold versus placebo | |
|---|---|---|---|
| Top 10: upregulated genes placebo versus TIFN101 | |||
| Immunoglobulin lambda variable 6–57 | IGLV6-57 | 0.01 | 1.63 |
| Putative V-set and immunoglobulin domain-containing protein 6-like | LOC642131 | 0.00 | 1.55 |
| Immunoglobulin lambda variable 7–46 (gene/pseudogene) | IGLV7-46 | 0.04 | 1.48 |
| Heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 | HS3ST3B1 | 0.00 | 1.41 |
| Interferon regulatory factor 4 | IRF4 | 0.00 | 1.40 |
| GDNF family receptor alpha 2 | GFRA2 | 0.00 | 1.40 |
| CD27 molecule | CD27 | 0.01 | 1.40 |
| CD79a molecule, immunoglobulin-associated alpha | CD79A | 0.03 | 1.38 |
| Plasminogen activator, tissue | PLAT | 0.00 | 1.37 |
| Der1-like domain family, member 3 | DERL3 | 0.00 | 1.37 |
| Top 10: downregulated genes placebo versus TIFN101 | |||
| Small nucleolar RNA, H/ACA box 38B (retrotransposed) | SNORA38B | 0.04 | −1.40 |
| Small nucleolar RNA, H/ACA box 21 | SNORA21 | 0.03 | −1.40 |
| Small nucleolar RNA, H/ACA box 60 | SNORA60 | 0.01 | −1.41 |
| Small nucleolar RNA, C/D box 53 | SNORD53 | 0.01 | −1.43 |
| Ephrin-A1 | EFNA1 | 0.00 | −1.45 |
| Small nucleolar RNA, C/D box 6 | SNORD6 | 0.02 | −1.46 |
| Small nucleolar RNA, H/ACA box 57 | SNORA57 | 0.00 | −1.47 |
| Small nucleolar RNA, H/ACA box 14B | SNORA14B | 0.00 | −1.73 |
| Family with sequence similarity 5, member C | FAM5C | 0.03 | −1.97 |
| Small Cajal body-specific RNA 4 | SCARNA4 | 0.00 | −2.00 |