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. 2017 Aug 23;5:75. doi: 10.3389/fcell.2017.00075

Figure 1.

Figure 1

Schematic of conventional and collagen-containing large COPII-vesicle formation. (A) Domain organization of the mammalian TANGO1 family. (B) In contrast to conventional COPII vesicles, the large COPII structure requires the TANGO1/cTAGE5/Sec12 complex, which efficiently activates Sar1 GTPase in the vicinity of forming large COPII structures.