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. 2017 Aug 22;8:432. doi: 10.3389/fneur.2017.00432

Table 2.

Values for late-stage PD patients are presented as median [IQR, 25th–75th percentile].

Parkinson’s disease patients (N = 24) Normal value
Respiratory support for speech
Vowel duration (s) 5.8 [4.4–11.5.8] 22.97 (1.1)b
Voice stability
Pitch break time (s) 1.24 [0.2–2.6.1] NAa
Jitter (%) 0.8 [0.5–1.1] ≤0.5–1%
Voice variability
Sentence F0SD (Hz) 2.4 [1.6–4] 2–4 Hz

Voice quality (Hz) Male (N = 14) Female (N = 10) Male Female

F0 125 [104–152] 202 [160–226.8] 128 (36)c 198 (44)c

Values for healthy subjects are presented as mean (SD), as reported in literature (2528).

F0, fundamental frequency; Sentence F0SD, SD of speaking F0 during sentences.

aNot available (healthy voices should have no trouble in maintaining voicing during a sustained vowel. Thus is 0% of voice breaks. No standard values are available).

bNormal value for vowel duration is referred to a healthy population aged between 71 and 80 years old.

cNormal value for voice quality is referred to a healthy population aged between 55 and 80 years old.