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. 2017 Aug 4;13(8):935. doi: 10.15252/msb.20167411

Figure 6. Using the enzyme‐constrained model for metabolic engineering applications.

Figure 6

  1. The physiological response of knocking out NDI1 can be reproduced using ecYeast7. Wild‐type and knockout experimental data are shown, together with model simulations (continuous and segmented lines, respectively).
  2. Succinate yield (grams of succinate per grams of substrate) versus biomass yield (grams of dry weight biomass per grams of substrate) simulations under batch conditions, compared with experimental data. Both glucose and ethanol phases are shown.
  3. Farnesene yield (grams of farnesene per grams of glucose) versus biomass yield (grams of dry weight biomass per grams of glucose) simulations under fed‐batch conditions, compared with experimental data.