Figure 3.

The effect of Tr14 on gene expression patterns after wounding. The RNA sequencing results were analyzed to identify transcripts that were differentially expressed between placebo-treated controls and Tr14-treated wounds, at each time point after injury (X axis). The effect of Tr14 on a given ontology is shown as an aggregate gene expression score of the differentially expressed transcripts in that GO group, expressed as the log2 ratio of the Tr14 vs. control levels, (Y axis, log2 ratio Tr14/Con). For the Muscle Contraction GO, a total of 25 transcripts were affected covering 17 unique, non-redundant genes. Tr14 affected 87 transcripts (51 genes) in the Response to Wounding GO, and 9 transcripts (6 genes) in the Response to Cytokine Stimulus GO.