Figure 6.

Muscle Contraction Gene Network at 96 h. Transcripts affected by Tr14 treatment were analyzed for their relevance to a series of pre-established biological pathways as described in Methods (Systems Biology). A greater than expected number of transcripts belonged to the Muscle Contraction pathway, which likely reflects wound contraction processes. In this pathway, reconstructed from the literature by Pathway Studio software (Nikitin et al., 2003), individual transcripts described by their standard gene symbol are connected by lines. Lines may connect genes if one gene product is known to induce the expression of another, if products interact directly, or if one product is a substrate for the other. Transcripts that are increased by Tr14 are highlighted in RED, while transcripts that decreased are shown in BLUE.