Table 1.
Top Gene Ontologies changed at each time point.
| Top 8 GO UP regulated | Top 8 GO DOWN regulated | |
|---|---|---|
| GO Term* | GO Term* | |
| 12 HR | immune response | regulation of system process |
| defense response | membrane depolarization | |
| response to wounding | regulation of muscle contraction | |
| cell activation | regulation of heart contraction | |
| inflammatory response | regulation of striated muscle contraction | |
| positive regulation of response to stimulus | regulation of interleukin-10 production | |
| cytokine-mediated signaling pathway | oxygen transport | |
| chemotaxis | regulation of interleukin-4 production | |
| 24 HR | cell adhesion | melanin biosynthetic process |
| biological adhesion | melanin metabolic process | |
| angiogenesis | nucleosome assembly | |
| vasculature development | chromatin assembly | |
| blood vessel development | chromatin assembly or disassembly | |
| blood vessel morphogenesis | nucleosome organization | |
| actin filament-based process | protein-DNA complex assembly | |
| regulation of cell proliferation | DNA packaging | |
| 36 HR | glycoprotein metabolic process | ectoderm development |
| vesicle-mediated transport | epidermis development | |
| blood vessel morphogenesis | keratinocyte differentiation | |
| blood vessel development | epithelial cell differentiation | |
| vasculature development | epidermal cell differentiation | |
| actin filament-based process | epithelium development | |
| biopolymer glycosylation | keratinization | |
| glycosylation | transition metal ion transport | |
| 72 HR | cell adhesion | ectoderm development |
| biological adhesion | epidermis development | |
| actin filament-based process | epithelial cell differentiation | |
| actin cytoskeleton organization | keratinocyte differentiation | |
| cytoskeleton organization | epidermal cell differentiation | |
| cell-cell adhesion | keratinization | |
| homophilic cell adhesion | transition metal ion transport | |
| membrane invagination | molting cycle | |
| 96 HR | cell adhesion | ectoderm development |
| biological adhesion | epidermis development | |
| phosphate metabolic process | keratinocyte differentiation | |
| phosphorus metabolic process | epidermal cell differentiation | |
| actin filament-based process | keratinization | |
| protein amino acid phosphorylation | epithelial cell differentiation | |
| homophilic cell adhesion | hair cycle | |
| actin cytoskeleton organization | molting cycle | |
| 120 HR | blood vessel development | ectoderm development |
| vasculature development | epidermis development | |
| protein amino acid phosphorylation | epithelial cell differentiation | |
| positive regulation of molecular function | epithelium development | |
| phosphate metabolic process | mesoderm development | |
| phosphorus metabolic process | keratinocyte differentiation | |
| enzyme linked receptor protein signaling pathway | epidermal cell differentiation | |
| angiogenesis | mesoderm formation | |
| 192 HR | vesicle-mediated transport | ectoderm development |
| phosphorus metabolic process | epidermis development | |
| phosphate metabolic process | keratinocyte differentiation | |
| protein amino acid phosphorylation | epithelial cell differentiation | |
| actin filament-based process | epidermal cell differentiation | |
| cell adhesion | translational initiation | |
| biological adhesion | mesoderm development | |
| homophilic cell adhesion | keratinization |
*
Ontologies presented in order of lowest to highest p-values of Top 8.