Fig. 4. : differences in the surface electrostatic potential of the inserted region of M8 metalloprotease family of Leishmania (Viannia) braziliensis. The location of the zinc ion is indicated for the crystal structure (PDBid: 1LML). The molecular surface is colored according to electrostatic potential using the Chimera software; where red, white and blue correspond to acidic, neutral and basic potentials, respectively. The identities of the subgroups previously obtained are given in the left margin of the figure.