Table 1.

Parameters of the 3D single cell migration model. (D: Derived, F: Fitted, M: model parameters)

Cell parameters
Cell radius	10 μm	M
Number of membrane elements per cell	128	M
Cytoskeletal string constant k	7.81E-2 nN/μm	D
req	3.52 μm	M
u0	0.75	M
ρ	2.03	M
Maximum interaction range Rmax	6.68 μm	M
Nucleus radius rn	3 μm	M
Number of integrin per element	250	F
Integrin binding rate	100/s	F
Focal adhesion parameters
LA	20 – 25 nm	[42, 43]
LN	5 nm	[43]
dA	55 nm	[44]
dN	5nm	[44]
Flow	10 pN	[45, 46]
FHigh	20–60 pN	[47–49]
T	30 seconds	[50]