TABLE 3.
Absolute size and rate of change over one year of the bone-cartilage-interface area (tAB) in a group without joint space narrowing (JSN, M0 / L0), groups with unilateral JSN (M1–3 / L0 and L1–3 / M0) and a group with bilateral JSN (M1–3 / L1–3).
| Area[mm2] | Change[mm2] | Change[%] | 95%CI[mm2] | SRM | p | |
|---|---|---|---|---|---|---|
| Medial Tibia (MT) | ||||||
| M0 / L0 | 1169.4 | 0.2 | 0.0 | 1.19 | 0.02 | 0.727 |
| M0 / L1–3 | 1221.3 | 1.7 | 0.1 | 2.63 | 0.13 | 0.193 |
| M1–3 / L0 | 1235.1 | 1.2 | 0.1 | 1.38 | 0.09 | 0.095 |
| M1–3 / L1–3 | 1266.3 | 0.9 | 0.1 | 6.82 | 0.08 | 0.786 |
| Central Medial Femur (cMF) | ||||||
| M0 / L0 | 559.7 | 1.4 | 0.3 | 0.92 | 0.15 | 0.003 |
| M0 / L1–3 | 593.3 | 2.0 | 0.3 | 1.98 | 0.20 | 0.043 |
| M1–3 / L0 | 608.6 | 1.7 | 0.3 | 1.05 | 0.16 | 0.002 |
| M1–3 / L1–3 | 626.9 | 6.2 | 1.0 | 4.94 | 0.76 | 0.018 |
| Lateral Tibia (LT) | ||||||
| M0 / L0 | 1003.4 | 1.2 | 0.1 | 1.14 | 0.01 | 0.047 |
| M0 / L1–3 | 1061.1 | 1.9 | 0.2 | 2.63 | 0.14 | 0.162 |
| M1–3 / L0 | 1034.0 | −0.8 | −0.1 | 1.29 | −0.07 | 0.206 |
| M1–3 / L1–3 | 1130.4 | −1.3 | −0.1 | 5.64 | −0.14 | 0.633 |
| Central Lateral Femur (cLF) | ||||||
| M0 / L0 | 617.9 | 0.1 | 0.0 | 0.89 | 0.01 | 0.873 |
| M0 / L1–3 | 661.2 | 2.6 | 0.4 | 1.68 | 0.30 | 0.003 |
| M1–3 / L0 | 641.4 | 1.2 | 0.2 | 0.92 | 0.13 | 0.011 |
| M1–3 / L1–3 | 675.9 | 1.0 | 0.1 | 6.82 | 0.09 | 0.764 |
SEM = standard error of the mean, SRM = standardized response mean, M0 = no medial joint space narrowing, M1–3 = medial joint space narrowing grade 1 to 3, L0 = no lateral joint space narrowing, L1–3 = lateral joint space narrowing grade 1–3