Table 2.

Occupational exposure to biocides and pesticides and risk of thyroid cancer.

Occupational exposure	Controls	Overall		Papillary		Well-differentiated
		Cases	OR* (95% CI)	Cases	OR* (95% CI)	Cases	OR* (95% CI)
Biocides
Never	262	201	1.00	169	1.00	198	1.00
Uncertain	146	137	1.30 (0.94–1.78)	116	1.34 (0.96–1.87)	130	1.26 (0.91–1.73)
Ever	88	121	1.65 (1.16–2.35)	104	1.67 (1.15–2.43)	117	1.61 (1.13–2.30)
Probability
Average
Low	30	32	1.21 (0.69–2.14)	44	1.15 (0.63–2.09)	52	1.17 (0.66–2.07)
Medium	28	45	2.03 (1.19–3.47)	72	2.03 (1.16–3.55)	84	1.95 (1.13–3.35)
High	30	44	1.76 (1.03–3.00)	93	1.90 (1.10–3.31)	101	1.76 (1.03–3.02)
Pfor trend**			0.16		0.082		0.11
Cumulative
Low	29	34	1.38 (0.78–2.42)	28	1.30 (0.72–2.35)	33	1.32 (0.75–2.32)
Medium	30	41	1.46 (0.85–2.50)	37	1.54 (0.88–2.69)	40	1.43 (0.83–2.46)
High	29	46	2.18 (1.28–3.73)	39	2.27 (1.30–3.97)	44	2.15 (1.25–3.70)
Pfor trend**			0.081		0.048		0.041
Intensity
Average
Low	30	38	1.44 (0.83–2.49)	30	1.27 (0.71–2.28)	36	1.34 (0.77–2.34)
Medium	39	60	1.87 (1.17–2.99)	54	2.06 (1.27–3.34)	59	1.86 (1.16–2.99)
High	19	23	1.54 (0.78–3.04)	20	1.55 (0.76–3.15)	22	1.52 (0.77–3.03)
Pfor trend**			0.91		0.73		0.82
Cumulative
Low	32	36	1.15 (0.67–1.99)	31	1.12 (0.63–1.99)	35	1.11 (0.64–1.92)
Medium	27	40	1.99 (1.14–3.47)	35	2.02 (1.13–3.60)	39	1.96 (1.12–3.42)
High	29	45	1.95 (1.14–3.34)	38	2.06 (1.17–3.60)	43	1.92 (1.12–3.31)
Pfor trend**			0.41		0.25		0.28
Pesticides
Never	385	347	1.00	301	1.00	339	1.00
Uncertain	100	125	1.19 (0.85–1.66)	84	1.09 (0.76–1.56)	100	1.16 (0.83–1.64)
Ever	11	7	0.95 (0.33–2.72)	4	0.52 (0.14–1.88)	6	0.84 (0.28–2.56)

^*Adjusted for age (continuous), gender, race, education, BMI, family history of thyroid cancer, history of benign thyroid disease, smoking status, alcohol consumption, and physical activity.

^**Calculated by continuous variables among exposed participants.