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Final model parameter estimates
| Parameters | Mean parameter estimate | 95 % confidence interval |
|---|---|---|
| V (L) | 1.58 | 1.29–1.87 |
| CL (L/h) | 0.0465 | 0.0392–0.0537 |
| θ | 10.8 | 5.50–15.7 |
| ω-BSV | ||
| V | 0.153 | −0.161 to 0.467 |
| CL | 0.205 | 0.054–0.356 |
| σ-RUV | 0.421 | 0.325–0.517 |
CL clearance, BSV between-subject variability, RUV residual unexplained variability, V volume of distribution, θ represents the model-estimated coefficient for the effect of gestational age (weeks) on darbepoetin alfa clearance
