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. 2017 Aug 25;7:9509. doi: 10.1038/s41598-017-10368-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Direct meta-analysis for disease-free survival and overall survival. (a) and (b) All patients. (c) and (d) According to cytogenetic risk groups. The size of the boxes is proportional to the amount of data contained in each data line. The bars indicate 95% confidence intervals (CIs). HDAraC, high-dose cytarabine (>2 g/m², ≤3 g/m² twice daily); IDAraC, intermediate-dose cytarabine (≥1 g/m², ≤2 g/m² twice daily); LDAraC, low-dose cytarabine (<1 g/m² twice daily); I–V = inverse variance. D + L = DerSimonan and Laird.