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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Ann Hematol. 2016 Aug 20;95(12):2009–2015. doi: 10.1007/s00277-016-2795-7

Table 5.

Toxicity Grade Hypoalbuminemia Normal p-value
ALT 0 15 (46.9) 49 (36.3) 0.40
1–2 14 (43.8) 76 (56.3)
3–4 3 (9.4) 10 (7.4)
AST 0 19 (59.4) 81 (60) > 0.99
1–2 12 (37.5) 49 (36.3)
3–4 1 (3.1) 5 (3.7)
GI 0 32 (100) 135 (100) >0.99
Leukopenia 0 6 (18.8) 52 (38.5) 0.08
1–2 8 (25) 29 (21.5)
3–4 18 (56.3) 54 (40)
Mucositis 0 27 (84.4) 108 (80) >0.99
1–2 5 (15.6) 23 (17)
3–4 0 (0) 4 (3)
Nephrotoxicity 0 24 (75) 106 (78.5) 0.65
1–2 7 (21.9) 21 (15.6)
3–4 1 (3.1) 8 (5.9)
Neutropenia 0 12 (37.5) 68 (50.4) 0.16
1–2 8 (25) 17 (12.6)
3–4 12 (37.5) 50 (37)
Pneumonitis 0 32 (100) 135 (100) 0.16
Bilirubin 0 23 (71.9) 118 (87.4) 0.001
1–2 5 (15.6) 17 (12.6)
3–4 4 (12.5) 0 (0)
Anemia 0 14 (43.8) 53 (39.3) 0.012
1–2 10 (31.3) 71 (52.6)
3–4 8 (25) 11 (8.1)