Table 5.
Toxicity | Grade | Hypoalbuminemia | Normal | p-value |
---|---|---|---|---|
ALT | 0 | 15 (46.9) | 49 (36.3) | 0.40 |
1–2 | 14 (43.8) | 76 (56.3) | ||
3–4 | 3 (9.4) | 10 (7.4) | ||
AST | 0 | 19 (59.4) | 81 (60) | > 0.99 |
1–2 | 12 (37.5) | 49 (36.3) | ||
3–4 | 1 (3.1) | 5 (3.7) | ||
GI | 0 | 32 (100) | 135 (100) | >0.99 |
Leukopenia | 0 | 6 (18.8) | 52 (38.5) | 0.08 |
1–2 | 8 (25) | 29 (21.5) | ||
3–4 | 18 (56.3) | 54 (40) | ||
Mucositis | 0 | 27 (84.4) | 108 (80) | >0.99 |
1–2 | 5 (15.6) | 23 (17) | ||
3–4 | 0 (0) | 4 (3) | ||
Nephrotoxicity | 0 | 24 (75) | 106 (78.5) | 0.65 |
1–2 | 7 (21.9) | 21 (15.6) | ||
3–4 | 1 (3.1) | 8 (5.9) | ||
Neutropenia | 0 | 12 (37.5) | 68 (50.4) | 0.16 |
1–2 | 8 (25) | 17 (12.6) | ||
3–4 | 12 (37.5) | 50 (37) | ||
Pneumonitis | 0 | 32 (100) | 135 (100) | 0.16 |
Bilirubin | 0 | 23 (71.9) | 118 (87.4) | 0.001 |
1–2 | 5 (15.6) | 17 (12.6) | ||
3–4 | 4 (12.5) | 0 (0) | ||
Anemia | 0 | 14 (43.8) | 53 (39.3) | 0.012 |
1–2 | 10 (31.3) | 71 (52.6) | ||
3–4 | 8 (25) | 11 (8.1) |