Table 4.
Logistic regression analyses of the association between CM and risk of clinically elevated TSH concentrations at each trimester.
| 1st Trimester | 2nd Trimester | 3rd Trimester | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| B (SE) | OR [95% CI] | B (SE) | OR [95% CI] | B (SE) | OR [95% CI] | |
|
| ||||||
| CM | 1.35 (0.7) | 3.84 [1.0–14.5]* | 1.94 (0.8) | 6.98 [1.4–36.0]* | 1.80 (0.8) | 6.07 [1.3–27.5]* |
|
| ||||||
| Race/ethnicity | ||||||
| Non-Hispanic White | 0.70 (0.8) | 2.01 [0.4–9.7] | 0.36 (1.1) | 1.43 [0.2–12.8] | 1.33 (1.1) | 3.80 [0.4–32.6] |
| Hispanic White | 0.20 (0.9) | 1.22 [0.2–7.3] | −0.82 (1.1) | 0.44 [0.1–3.5] | 0.48 (1.1) | 1.61 [0.2–13.2] |
|
| ||||||
| Education | 0.22 (0.4) | 1.25 [0.6–2.6] | −1.31 (0.5) | 0.27 [0.1–0.7]* | −0.18 (0.4) | 0.84 [0.4–1.9] |
|
| ||||||
| Nulliparity | 2.66 (1.7) | 14.3 [1.5–139.9]* | 2.23 (1.2) | 9.29 [0.9–88.3] | 2.69 (1.2) | 14.7 [1.3–166.1]* |
|
| ||||||
| Primiparity | 1.77 (1.2) | 5.86 [0.5–62.6] | 1.82 (1.2) | 6.19 [0.6–64.8] | 2.10 (1.3) | 8.16 [0.7–97.8] |
|
| ||||||
| Pre-pregnancy BMI | 1.19 (0.7) | 3.30 [0.9–12.8] | 1.97 (0.9) | 7.14 [1.1–45.4]* | 1.36 (0.8) | 3.90 [0.8–19.8] |
|
| ||||||
| Childhood SES | 0.08 (0.1) | 1.08 [0.9–1.3] | −0.06 (0.1) | 0.94 [0.7–1.2] | −0.04 (0.1) | 0.96 [0.8–1.2] |
|
| ||||||
| Depression (CES-D) | 0.34 (0.8) | 1.40 [0.3–7.1] | −1.05 (1.1) | 0.35 [0.0–3.1] | −0.68 (1.0) | 0.51 [0.1–3.8] |
Note. BMI = body mass index; CM = childhood maltreatment; SES = Socio-economic status; CES-D = Center for Epidemiological Studies–Depression scale. BMI is dichotomized in normal weight (BMI < 25 and > 18.5) vs. overweight/obesity (BMI > 25). Logistic regressions were performed separately for each trimester. R2 = .27–.37 (Nagelkerke).
*
p < .05