Skip to main content
. Author manuscript; available in PMC: 2017 Aug 28.
Published in final edited form as: Dev Biol. 2016 Jun 10;416(1):111–122. doi: 10.1016/j.ydbio.2016.05.038

Fig. 3.

Fig. 3

Laterality is likely established in Pofut2 epiblast mutants. Representative whole mount Lefty2 in situ hybridization in E8.5 embryos viewed from the left side (anterior to the left) (A–E) or the anterior (A′–E′). The number of Pofut2 wild-type (Pofut2 wt) or Pofut2 epiblast mutant (Pofut2 epi mut) embryos displaying the respective expression pattern is shown as a fraction of total embryos analyzed. (A) In wild-type embryos Lefty2 was expressed in the lateral plate mesoderm or 5 embryos and extinguished in 7. (B–E) A range of Lefty2 expression in the lateral plate mesoderm was detected in the majority of Pofut2 epiblast mutant embryos. Genotype of epiblast (Epi:) and extraembryonic tissues (Ext:) are shown for each embryo.