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Forepaw mechanical hyperalgesia in response to von Frey filament stimulation. Injury with vehicle injection (vehicle injury) exhibits significantly reduced response thresholds starting at day 1 and persisting until day 7 compared to both IB4-SAP injury and IB4-SAP sham (*p<0.00003). IB4-SAP injury is not different from IB4-SAP sham on any day. Data are reported as the mean±standard deviation.
