Figure 5. IL-2 and IL-10 expression in the lung during infection after administration of PA-824, CS or the combination of both. The mice lungs after treatment were stripped out and prepared for analysis. A, mRNA expression level of IL-2 and IL-10 in the mice lung by real-time PCR. B, Protein immunoblots and quantification of IL-2 and IL-10 in M.tb infected mice lungs after treatment. GAPDH acted as an internal control. CS: Cordyceps sinensis (Berk.) Sacc.; M.tb: Mycobacterium tuberculosis; IL-2: interleukin-2; IL-10: interleukin-10. *P<0.05, **P<0.01, ***P<0.001, compared to control (ANOVA).
