Figure 2.

Relative activities of CHGA promoter haplotypes in different cell lines. A, schematic representation of the CHGA promoter haplotype-reporter constructs cloned into pGLuc-basic vector. B and C, differential promoter activities of CHGA promoter haplotype–reporter constructs. CHGA promoter haplotype–reporter constructs were transfected into human neuroblastoma cell lines IMR-32 and SH-SY5Y along with β-galactosidase expression plasmid. Results are expressed as mean ± S.E. of triplicate values of the ratio of Gaussia luciferase/β-gal. ***, p < 0.001 and ****, p < 0.0001 as compared with Hap2–GLuc construct.