TABLE 1.

Summary of asbestos-related disease clinicopathological studies that compared imaging and autopsy findings

First author [ref.]	Study population	Methods compared	Findings
Asbestosis
Kipen [15]	138 deceased insulation workers with primary lung carcinoma	Radiology, biopsy and autopsy	False-negative: 18.1%
Sluis-Cremer [20]	172 deceased asbestos mineworkers	Radiological findings of three readers and autopsy	67 (39.0%) autopsy-diagnosed asbestosis cases; for readers 1, 2 and 3, respectively:# true-positive: 38, 18 and 30; false-positive: 25, 5 and 21; false-negative: 29, 49 and 36; true-negative: 80, 100 and 84; sensitivity: 56.7%, 26.9% and 45.5%; specificity: 76.2%, 95.2% and 80.0%
Akira [17]	7 deceased asbestos workers with radiologically diagnosed asbestosis	HRCT, biopsy and autopsy	Good correlation between HRCT and autopsy findings
Mizell [16]	273 deceased asbestos workers with radiologically diagnosed asbestosis	Radiology and autopsy	True-positive: 36.8% (89 out of 242 in study group); false-positive: 63.2% (153 out of 242 in study group)
Mesothelioma
Yates [19]	272 deceased cases with suspected or confirmed mesothelioma	Clinical features, radiology and autopsy	True-positive: 99.2% (265 out of 267 autopsies)
Takeshima [18]	382 deceased cases with clinically diagnosed mesothelioma	Clinical features, radiology, pathology and autopsy	True-positive: 74.3% for males and 59.2% for females

HRCT: high-resolution computed tomography. ^#: values derived from Sluis-Cremer et al. [20].