Table 2.

Number of tissue HER-2-positive patients with elevated or normal serum HER-2, cfHER-2 DNA and cfB2M DNA levels prior to metastases detection

Serum HER-2 prior to metastases detection (tissue-positive)	With metastases	Without metastases	Total
Elevated	8	3	11
Normal	7	29	36
Total	15	32	47
CfHER-2 DNA prior to metastases detection (tissue-positive)	With metastases	Without metastases	Total
Elevated	8	9	17
Normal	7	23	30
Total	15	32	47
CfB2M DNA prior to metastases detection (tissue-positive)	With metastases	Without metastases	Total
Elevated	6	9	15
Normal	9	23	32
Total	15	32	47