Table 2.
Parameters of enzymatic antioxidant status (superoxide dismutase (SOD), its isoenzymes: manganese superoxide dismutase (SOD-Mn) and copper-zinc superoxide dismutase (SOD-CuZn), catalase (CAT), glutathione peroxidase (GPx), and glutathione reductase (GR) activity) and nonenzymatic antioxidant status (ferric reducing ability of plasma (FRAP), protein sulfhydryl (PSH), and uric acid (UA) concentration, as well as activity of ceruloplasmin (CER)) in ankylosing spondylitis (AS) patients and healthy subjects.
| Parameter | AS patients (n = 48) | Healthy subjects (n = 48) | p |
|---|---|---|---|
| SOD (p) (NU/ml) | 12.67 ± 1.98 | 10.93 ± 2.55 | <0.001 |
| SOD-Mn (p) (NU/ml) | 5.08 ± 2.00 | 4.59 ± 1.88 | 0.223 |
| SOD-CuZn (p) (NU/ml) | 7.64 ± 2.31 | 6.79 ± 1.99 | 0.055 |
| SOD (e) (NU/mgHb) | 105.85 ± 22.60 | 95.50 ± 19.18 | 0.017 |
| CAT (e) (IU/mgHb) | 410.98 ± 63.56 | 352.55 ± 77.21 | <0.001 |
| GPx (e) (IU/gHb) | 27.23 ± 6.43 | 24.49 ± 5.00 | 0.022 |
| GR (e) (IU/gHb) | 1.67 ± 0.58 | 1.38 ± 0.43 | 0.007 |
| FRAP (p) (μmol/l) | 550.38 ± 76.98 | 642.17 ± 105.67 | <0.001 |
| PSH (s) (μmol/l) | 474.46 ± 192.06 | 559.07 ± 215.14 | 0.045 |
| UA (s) (mg/dl) | 4.73 ± 1.39 | 5.84 ± 1.53 | <0.001 |
Values are expressed as means ± standard deviations (SD) of the means; p: plasma; s: serum; e: erythrocyte lysates.