Table 2. Factors that affect toxicity in pelvis radiotherapy.

	Acute toxicity (grade ≥ 2)			Chronic toxicity
Factors	Univariate (p)	HR (95% CI)	Multivariate (p)	Univariate (p)	HR (95% CI)	Multivariate (p)
Age, year (≤ 55 vs > 55)	0.09			0.53
Cancer type	0.00		0.001	0.004		0.27
Uterine cervical		1.00 (referent)			1.00 (referent)
Endometrial		0.02 (0.002–0.23)			0.24 (0.04–1.36)
Bladder		0.00			0.00
ECOG (0–1 vs 2–3)	0.70			0.96
Stage (I-II vs III-IV)	0.32			0.12
Histology	0.003		0.19	0.08	0.76
Adenocarcinoma		1.00 (referent)			1.00 (referent)
Squamous cell carcinoma		0.41 (0.13–1.30)			0.64 (1.93–2.10)
Pre-RT surgery	0.07	1.48 (0.49–4.52)	0.49	0.45
Pre-RT chemotherapy	0.16			0.66
Concurrent chemotherapy	0.00	0.02 (0.95–5.15)	0.06	0.65
Radiotherapy dose	0.03		0.52	0.70
< 50.4 Gy		1.00 (referent)
50.4 Gy		0.45 (0.11–1.80)
> 50.4 Gy		0.49 (0.09–2.79)
Radiotherapy field	0.86			0.73
Boost radiotherapy	0.89			0.72
Radiotherapy modality	0.003		0.01	0.12		0.22
IMRT		1.00 (referent)			1.00 (referent)
cRT		3.39 (1.20–6.43)			1.70 (0.72–3.98)