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. Author manuscript; available in PMC: 2018 Mar 8.
Published in final edited form as: Sci Transl Med. 2017 Mar 8;9(380):eaaf5347. doi: 10.1126/scitranslmed.aaf5347

Fig. 2. Differential immune recognition of synthetic ST8 CPS frameshift oligosaccharides 1–4.

Fig. 2

(A) Glycan microarray analysis of pooled sera from Pneumovax 23-vaccinated humans (human reference serum mixture 007sp), rabbit ST8 typing serum, and a protective murine mAb 28H11 at different concentrations. Corresponding data are means + SD of 8 spots as technical replicates. (B) Inhibition of antibody binding by pre-adsorption with native ST8 CPS. Data are means + SD of 8 spots as technical replicates. P values are determined by one-tailed, unpaired t test with Welch’s correction. Data are from one representative out of at least 2 independent experiments. MFI, mean fluorescence intensity. n.s., not significant.