Table 1.
Cells used in this study. The table shows the name of cell lines, their mutations, immortalization conditions, the nucleotide sequence of the stop codon mutation and immediately following, and whether the cell line responded to read-through treatment.
| Cell line name | Mutation | Condition | Stop codon | Nucleotide after PTC | Read-through |
|---|---|---|---|---|---|
| RDEB53K | p.R669X/p.R669X | HpV immortalized, cSCC | C->T TGA |
G | NO |
| RDEB14K | p.Q251X/p.Q251X | HpV immortalized | C->T TAG |
T | YES |
| RDEB13K | p.G2073D/p.R578X | HpV immortalized | C->T TGA |
G | YES |
| RDEB101K/F | p.R669X/p.R669X | Primary, HpV immortalized | C->T TGA |
G | NO |
| RDEB102K/F | p.R2814X/p.R2814X | Primary, HpV immortalized | C->T TGA |
C | YES |
| RDEB5K | p.R578X/p.Q906X | Primary | C->T TGA/TAG |
G/G | YES |
| RDEB3K | p.R525X/- | cSCC | C-> T TGA |
G | NO |
| RDEB107F | p.R578X/p.R2492X | HpV immortalized | C->T TGA/TGA |
G/G | NO |
| RDEB111K | p.R2610X/p.R2610X | HpV immortalized | C->T TGA |
G | YES |
| RDEB112K | p.R1343X/p.R2069C | HpV immortalized | C->T TGA |
G | YES |
| RDEB110K | p.R2338X/p.R2338X | HpV immortalized | C->T TGA/TGA |
G | NO |
| RDEB113K | p.R1630X/p.R2069C | HpV immortalized | C->T TGA |
G | YES |
| RDEB115K | c.4249delG/p.R1933X | HpV immortalized | C->T TGA |
G | YES |
| RDEB116K | p.R1933X/p.R1933X | HpV immortalized | C->T TGA |
G | NO |