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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Mayo Clin Proc. 2017 May;92(5):838–850. doi: 10.1016/j.mayocp.2017.02.003

TABLE 1.

Clinical Presentation of Peripheral Neuropathy in Plasma Cell Disorders

  1. Monoclonal Gammopathy Associated Peripheral Neuropathy

    1. Monoclonal gammopathy of undetermined significance (MGUS)

      • IgM

      • Non-IgM: IgG, IgA

    2. Multiple Myeloma (including smoldering multiple myeloma)

    3. Waldenstrom Macroglobulinemia

  2. POEMS Syndrome

  3. Systemic immunoglobulin light chain amyloidosis

  4. Unrelated (coincidental neuropathy in patients with a monoclonal protein)

Ig, immunoglobulin; POEMS, polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes.