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. 2017 Aug 25;7:9548. doi: 10.1038/s41598-017-10328-8

Table 2.

Univariate and multivariate Cox proportional hazards analysis of progression-free survival.

Variable HR Univariate P value HR Multivariate P value
95% CI 95% CI
Age (years) (≤50 vs. >50) 0.990 0.756–1.298 0.945
FIGO stage (I/II/III/IV) 2.390 1.966–2.907 <0.001 1.478 1.170–1.868 0.001
Histological grade (G1/G2/G3) 1.146 0.973–1.350 0.102
Histological subtype (serous vs. non-serous) 1.075 0.802–1.441 0.629
Residual tumor mass (≤2 cm vs. >2 cm) 3.500 2.582–4.744 <0.001 1.471 1.009–2.144 0.045
Ascites (yes vs. no) 2.127 1.603–2.821 <0.001
CA-125 (U/ml) (<35 vs. ≥35) 2.025 1.267–3.236 0.003
Chemosensitivity (sensitive vs. resistant) 8.390 6.066–11.605 <0.001 7.427 4.891–11.278 <0.001
mGPS (0/1/2) 1.750 1.470–2.083 <0.001 1.327 1.053–1.673 0.017
PNI (<47.2 vs. ≥ 47.2) 2.411 1.807–3.216 <0.001 2.096 1.380–3.185 0.001
CAR (<0.5 vs. ≥ 0.5) 1.751 1.326–2.312 <0.001
LMR (<3.82 vs. ≥ 3.82) 2.271 1.702–3.030 <0.001
BMI (<18.5 vs. ≥ 18.5) 2.615 1.746–3.917 <0.001 1.828 1.155–2.895 0.010

CAR, C-reactive protein/albumin ratio; BMI, body mass index; FIGO, Federation of Gynecologists and Obstetricians; LMR, lymphocyte/monocyte ratio; mGPS, modified Glasgow prognostic score; PNI, prognostic nutritional index.