Table 3.
Concentrations of urinary metabolites (specific gravity adjusted) of polycyclic aromatic hydrocarbons among exposed and unexposed groups.
All participants | Chimney sweeps | Controls | |||||||
---|---|---|---|---|---|---|---|---|---|
n e | Median | Min | Max | n e | Median | Min | Max | P f | |
1-OH-PYRa | 148 | 0.56 | 0.03 | 7.49 | 151 | 0.07 | 0.00 | 1.25 | <0.001 |
2-OH-PHb | 148 | 0.78 | 0.09 | 14.56 | 151 | 0.18 | 0.05 | 4.01 | <0.001 |
3-OH-BaPc | 132 | 4.75 | 0.00 | 42.86 | 130 | 1.38 | 0.00 | 16.51 | <0.001 |
3-OH-BaAd | 142 | 6.28 | 0.46 | 71.70 | 144 | 1.99 | 0.04 | 20.88 | <0.001 |
Only non-smokers | |||||||||
1-OH-PYR | 95 | 0.50 | 0.03 | 7.17 | 123 | 0.07 | 0.005 | 0.53 | <0.001 |
2-OH-PH | 95 | 0.68 | 0.09 | 14.56 | 123 | 0.16 | 0.05 | 4.01 | <0.001 |
3-OH-BaP | 90 | 4.18 | 0.00 | 31.89 | 105 | 1.18 | 0.00 | 16.51 | <0.001 |
3-OH-BaA | 92 | 5.53 | 0.46 | 71.70 | 117 | 1.80 | 0.04 | 8.12 | <0.001 |
a1-hydroxypyrene (µg/L), b2-hydroxyphenanthrene (µg/L), c3-hydroxybenzo[a]pyrene (ng/L). d3-hydroxybenzo[a]anthracene (ng/L). eThe number of samples with valid concentrations for 3-OH-BaP and 3-OH-BaA was lower, compared with other two metabolites, due to their low concentrations in urine. fGeneral linear model adjusted for age, BMI and smoking status.