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. 2017 Aug 25;7:9408. doi: 10.1038/s41598-017-09686-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Desktop bioreactor platform for perfused microtumour culture. Syringe pumps are used to provide a continuous flow which allows a consistent nutrient supply to the Bioreactor. A syringe aligner allows delivery of therapeutics to the flow. The bioreactor can be mounted on a normal fluorescence microscope (upper left corner photograph) for real-time imaging. The design of the upstream input and downstream analysis is highly modular which allows other users to integrate their own apparatus into the design.